NAD3® | Anti-Aging

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S(9) Sirtuin Booster

S(9) Sirtuin Booster

A High Performance Nutrition Formulation, S9® Sirtuin Booster™

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Is NAD3 safe?

Absolutely. NAD3 is a clinically tested blend of three all-natural ingredients, and is manufactured in an FDA-approved lab without drugs or stimulants. While it is generally well-tolerated, consult your doctor if you have any concerns or pre-existing conditions.

How long does it take for NAD3 to work?

Many users start noticing increased energy and improved focus within 24 hours. Significant benefits, like lowering LDL cholesterol and boosting stem cell levels, typically become noticeable within 7 to 12 weeks.

What can I expect from taking NAD3?

NAD3 offers a wide range of health benefits, including elevated energy levels, improved metabolic health, reduced inflammation, enhanced cellular function, and protection against age-related diseases.

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ONE DAILY SERVING
The Purest Nutrients, In Perfect Harmony
working together to change how we age
Here’s what to expect:
Red Bullet
Support healthy cardiovascular health by lowering LDL Cholesterol
Red Bullet
Improve recovery time from physical activity and/or injury
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Combat inflammation induced aging on a cellular level
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Elevate energy levels without the use of stimulants or synthetic
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Promote a healthy metabolism and better nutrient absorption
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Improve on your sleep. Wake up feeling for refined and refreshed
Overlapping Image

only $1.27 a day

What would you
do for better health?

With one single serving of NAD3, you’ll experience these real world benefits!

Lower LDL Image
Lower LDL Cholesterol and Triglycerides in just 12 weeks. This is Clinically proven through Human Trials. Learn more about it here.
Click to learn more
Boost Stem Cells Image
Boost Stem Cell levels in just 3 Days helping you recover faster from fall or injury. This is Clinically proven through Human Trials. Learn more about it here. Learn more about it here.
Click to learn more
Elevate NAD Levels Image
Elevate your NAD+ levels within 24 hours of taking NAD3. This will give you All-Day energy! Learn more about how NAD3 is a superior NAD+ Booster® Learn more about how NAD3 is a superior NAD+ Booster®
Click to learn more
Activate NLRP3 Image
Something no other NAD+ supplement can do, and that’s activating NLRP3 to lower your inflammation like never before. Learn more about the science. Learn more about the science.
Click to learn more
Overlapping Image TRY NAD3 RISK FREE
MONEY BACK GUARANTEE
A Message From
Dr. Michael Setareh
Medical Director, TRU MD
  • Backed by Real Science
  • Doctor Recommended
  • Clinically Proven Human Trials
TRY NAD3 RISK FREE
MONEY BACK GUARANTEE
Dr. Michael Setareh
Medical Director, TRU MD
Boost NAD+ Levels within 24 hours!(More Energy)
Boost NAD+ Levels within 24 hours!(More Energy)
Boosting NAD+ is crucial to cellular health. But elevating NAD+ levels is just one part of the equation. Mitochondrial capacity is measured by how much output (ATP) your cells produce. NAD3 has clinically shown to increase Mitochondrial capacity by 50% over the standard NAD+ supplement. Along with boosting NAD+ levels, NAD3 activates localized mitochondrial sirtuins SIRT3, SIRT4, and SIRT5. This group of sirtuins is known to suppress the emergence of diverse age-related pathologies: hearing loss, cardiac fibrosis, and malignancy. Studies show that boosting mitochondrial function rejuvenates your cells so they start operating as if they were younger cells again. Along with this comes a surge of controlled energy. Unlike that from caffeinated drinks, the energy from NAD3 is pure, similar to that energy you had when you were young*.
Higher Stem Cell Levels in 3 Days (Heal Faster)
Higher Stem Cell Levels in 3 Days (Heal Faster)
Stem cells are crucial for healing due to their unique abilities to regenerate and differentiate into various cell types, replace damaged cells, and promote tissue repair. Their plasticity allows them to transform into different cell types needed for specific tissues, while their paracrine effects involve secreting growth factors and cytokines that reduce inflammation and enhance repair. Additionally, stem cells have anti-inflammatory properties that modulate the immune response and prevent further damage, promote the formation of healthy tissue over scar tissue, and accelerate the healing process, leading to better functional outcomes and faster recovery. These properties make stem cells a vital focus in regenerative medicine and therapeutic treatments for various injuries and diseases.
Lower LDL Cholesterol & Triglycerides in 3 Weeks!
Lower LDL Cholesterol & Triglycerides in 3 Weeks!
Lowering LDL cholesterol and triglycerides with NAD3 offers significant health benefits, including reduced risk of cardiovascular disease, improved blood vessel health, and enhanced metabolic health. By preventing plaque buildup in arteries and improving blood flow, it lowers the risk of heart attacks and strokes. Additionally, healthy lipid levels aid in better weight management, reduce the risk of obesity-related issues, and prevent fatty liver disease, promoting better liver function. These improvements contribute to increased longevity and a higher quality of life. NAD3 supports these benefits by enhancing cellular energy production, promoting healthy lipid metabolism, and reducing inflammation, making it a valuable supplement for cardiovascular and metabolic health.
5x More Effective in Cellular Health
5x More Effective in Cellular Health
NAD3 is five times more effective in promoting cellular health due to its comprehensive mechanism of action that includes activating NAD+ levels, which is crucial for cellular energy production and DNA repair. It also activates Sirtuins, a family of proteins that play a key role in aging, inflammation reduction, and metabolic regulation. Additionally, NAD3 lowers NLRP3, a component of the inflammasome linked to chronic inflammation and various diseases. It further boosts NRF-2, a protein that regulates antioxidant responses and protects against oxidative stress, and activates the P27 protein, which is involved in cell cycle regulation and preventing abnormal cell growth. Together, these actions make NAD3 a powerful enhancer of cellular health, offering robust protection and improvement of cellular functions.
Reduces NLRP3 to lower Cellular Inflammation
Reduces NLRP3 to lower Cellular Inflammation
Lowering NLRP3 levels with NAD3 offers substantial health benefits, primarily by reducing chronic inflammation, which is a key factor in the development of numerous diseases, including cardiovascular diseases, neurodegenerative disorders, and autoimmune conditions. NLRP3 is a crucial component of the inflammasome, a protein complex that triggers inflammatory responses. By inhibiting NLRP3, NAD3 helps to prevent the excessive activation of the immune system, thereby minimizing tissue damage and inflammation. This reduction in inflammation can lead to improved overall health, enhanced immune system balance, and a lower risk of chronic diseases. Additionally, by managing NLRP3 levels, NAD3 supports better cellular health and longevity, promoting a healthier, more resilient body.
Dr. Michael Setareh
Medical Director, TRU MD
Boost NAD+ Levels within 24 hours!(More Energy)
Boost NAD+ Levels within 24 hours!(More Energy)
Boosting NAD+ is crucial to cellular health. But elevating NAD+ levels is just one part of the equation. Mitochondrial capacity is measured by how much output (ATP) your cells produce. NAD3 has clinically shown to increase Mitochondrial capacity by 50% over the standard NAD+ supplement. Along with boosting NAD+ levels, NAD3 activates localized mitochondrial sirtuins SIRT3, SIRT4, and SIRT5. This group of sirtuins is known to suppress the emergence of diverse age-related pathologies: hearing loss, cardiac fibrosis, and malignancy. Studies show that boosting mitochondrial function rejuvenates your cells so they start operating as if they were younger cells again. Along with this comes a surge of controlled energy. Unlike that from caffeinated drinks, the energy from NAD3 is pure, similar to that energy you had when you were young*.
Higher Stem Cell Levels in 3 Days (Heal Faster)
Higher Stem Cell Levels in 3 Days (Heal Faster)
Stem cells are crucial for healing due to their unique abilities to regenerate and differentiate into various cell types, replace damaged cells, and promote tissue repair. Their plasticity allows them to transform into different cell types needed for specific tissues, while their paracrine effects involve secreting growth factors and cytokines that reduce inflammation and enhance repair. Additionally, stem cells have anti-inflammatory properties that modulate the immune response and prevent further damage, promote the formation of healthy tissue over scar tissue, and accelerate the healing process, leading to better functional outcomes and faster recovery. These properties make stem cells a vital focus in regenerative medicine and therapeutic treatments for various injuries and diseases.
Lower LDL Cholesterol & Triglycerides in 3 Weeks!
Lower LDL Cholesterol & Triglycerides in 3 Weeks!
Lowering LDL cholesterol and triglycerides with NAD3 offers significant health benefits, including reduced risk of cardiovascular disease, improved blood vessel health, and enhanced metabolic health. By preventing plaque buildup in arteries and improving blood flow, it lowers the risk of heart attacks and strokes. Additionally, healthy lipid levels aid in better weight management, reduce the risk of obesity-related issues, and prevent fatty liver disease, promoting better liver function. These improvements contribute to increased longevity and a higher quality of life. NAD3 supports these benefits by enhancing cellular energy production, promoting healthy lipid metabolism, and reducing inflammation, making it a valuable supplement for cardiovascular and metabolic health.
5x More Effective in Cellular Health
5x More Effective in Cellular Health
NAD3 is five times more effective in promoting cellular health due to its comprehensive mechanism of action that includes activating NAD+ levels, which is crucial for cellular energy production and DNA repair. It also activates Sirtuins, a family of proteins that play a key role in aging, inflammation reduction, and metabolic regulation. Additionally, NAD3 lowers NLRP3, a component of the inflammasome linked to chronic inflammation and various diseases. It further boosts NRF-2, a protein that regulates antioxidant responses and protects against oxidative stress, and activates the P27 protein, which is involved in cell cycle regulation and preventing abnormal cell growth. Together, these actions make NAD3 a powerful enhancer of cellular health, offering robust protection and improvement of cellular functions.
Reduces NLRP3 to lower Cellular Inflammation
Reduces NLRP3 to lower Cellular Inflammation
Lowering NLRP3 levels with NAD3 offers substantial health benefits, primarily by reducing chronic inflammation, which is a key factor in the development of numerous diseases, including cardiovascular diseases, neurodegenerative disorders, and autoimmune conditions. NLRP3 is a crucial component of the inflammasome, a protein complex that triggers inflammatory responses. By inhibiting NLRP3, NAD3 helps to prevent the excessive activation of the immune system, thereby minimizing tissue damage and inflammation. This reduction in inflammation can lead to improved overall health, enhanced immune system balance, and a lower risk of chronic diseases. Additionally, by managing NLRP3 levels, NAD3 supports better cellular health and longevity, promoting a healthier, more resilient body.
This Is Why NAD3 is Better Than The Rest
Never mind the fact we’re the only NAD+ Booster® Dietary Supplement proven to work with real life benefits
(And not just some numbers on a graph)
This Is Why NAD3 is Better Than The Rest
This Is Why NAD3 is Better Than The Rest
Never mind the fact we’re the only NAD+ Booster® Dietary Supplement proven to work with real life benefits
(And not just some numbers on a graph)
NAD3 Product
This Is Why NAD3 is Better Than The Rest
RECOMMENDED BY
Top Medical Experts & Pro Athletes
Dr. Michael Setareh
Dr. Michael Setareh
Board Certified Medical Doctor & Medical Director | TRU MD

“This is the most innovative supplement on the market to date.If I had to pick only one supplement to take daily, it would be NAD3.I take it. My patients take it. It’s a life changing product.”

Dr. Martina Randall
Dr. Martina Randall
Board-Certified Foot and Ankle Surgeon | Sports Medicine Specialist

“NAD3 is the perfect addition to any self-care routine.While treatments like massages or stretches focus on the surface, NAD3 works from within to support bone strength, joint mobility, and reduce inflammation—keeping you active and resilient.A must-have for true rejuvenation.”

Nick Urankar
Nick Urankar
5x CrossFit Games Athlete & CEO of The Zeus Method

“When it comes to performing at the peak of your abilities, every choice matters.That’s why my partnership with HPN isn’t just another endorsement.It’s a testament to our shared values.”

Clark Bartram
Clark Bartram
America’s Most Trusted Fitness Expert & CEO of The CBX Method

“With age comes wisdom, but with wisdom should also come clarity.HPN’s commitment to quality echoes my philosophy:Embrace age with strength and vitality.”

Frank Medrano
Frank Medrano
World Renowned Calisthenics Expert & CEO of The BluePrint

“HPN aligns perfectly with my dedication to holistic fitness.Their high-quality supplements resonate deeply with my philosophy:mastery through clean, effective, and innovative approaches.”

RECOMMENDED BY
Top Medical Experts & Pro Athletes
Dr. Michael Setareh
Dr. Michael Setareh
Board Certified Medical Doctor & Medical Director | TRU MD

“This is the most innovative supplement on the market to date.If I had to pick only one supplement to take daily, it would be NAD3.I take it. My patients take it. It’s a life changing product.”

Dr. Martina Randall
Dr. Martina Randall
Board-Certified Foot and Ankle Surgeon | Sports Medicine Specialist

“NAD3 is the perfect addition to any self-care routine.While treatments like massages or stretches focus on the surface, NAD3 works from within to support bone strength, joint mobility, and reduce inflammation—keeping you active and resilient.A must-have for true rejuvenation.”

Nick Urankar
Nick Urankar
5x CrossFit Games Athlete & CEO of The Zeus Method

“When it comes to performing at the peak of your abilities, every choice matters.That’s why my partnership with HPN isn’t just another endorsement.It’s a testament to our shared values.”

Clark Bartram
Clark Bartram
America’s Most Trusted Fitness Expert & CEO of The CBX Method

“With age comes wisdom, but with wisdom should also come clarity.HPN’s commitment to quality echoes my philosophy:Embrace age with strength and vitality.”

Frank Medrano
Frank Medrano
World Renowned Calisthenics Expert & CEO of The BluePrint

“HPN aligns perfectly with my dedication to holistic fitness.Their high-quality supplements resonate deeply with my philosophy:mastery through clean, effective, and innovative approaches.”