ONE DAILY SERVING

The Purest Nutrients, In Perfect Harmony

working together to change how we age

Here's what to expect:

Support healthy cardiovascular health by lowering LDL Cholesterol

Improve recovery time from physical activity and/or injury

Combat inflammation induced aging on a cellular level

Elevate energy levels without the use of stimulants or synthetic

Promote a healthy metabolism and better nutrient absorption

Improve on your sleep. Wake up feeling for refined and refreshed

only $1.27 a day

What would you
do for better health?

With one single serving of NAD3, you'll experience these real world benefits!

Lower LDL Cholesterol and Triglycerides in just 12 weeks. This is Clinically proven through Human Trials. Learn more about it here.

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Boost Stem Cell levels in just 3 Days helping you recover faster from fall or injury. This is Clinically proven through Human Trials. Learn more about it here.

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Elevate your NAD+ levels within 24 hours of taking NAD3. This will give you All-Day energy! Learn more about how NAD3 is a superior NAD+ Booster®

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Something no other NAD+ supplement can do, and that's activating NLRP3 to lower your inflammation like never before. Learn more about the science.

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MONEY BACK GUARANTEE

HUMAN TRIALS AVAILABLE

Findings showed that NAD3® significantly improved total cholesterol, LDL cholesterol, and the LDL ratio, marking one of the most impressive human trial outcomes in the last decade. In the study, participants took NAD3® for 12 weeks. Blood samples were collected in the morning after an overnight fast, both before starting NAD3® and after completing the 12-week program. The measurements focused on total cholesterol, LDL cholesterol, and HDL cholesterol. Lowering cholesterol levels is beneficial because it reduces the risk of cardiovascular diseases, including heart attacks and strokes, by preventing the buildup of plaque in the arteries. Additionally, maintaining healthy cholesterol levels can improve overall heart health and enhance longevity.

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HUMAN TRIALS AVAILABLE

In a groundbreaking development, the College of Health Sciences at the University of Memphis, has revealed the remarkable effects of NAD3® supplementation on adult stem cell circulation in healthy individuals aged 40-70. This pivotal study demonstrates NAD3®'s potential to modulate stem cell populations, opening a promising pathway towards harnessing regenerative medicine to combat aging. Boosting stem cell levels with NAD3® can enhance tissue repair, improve organ function, and promote overall longevity by increasing the body's ability to regenerate and heal. This advancement in stem cell modulation offers significant implications for maintaining health and vitality as we age.

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HUMAN TRIALS AVAILABLE

Elevating NAD+ levels is essential for maintaining cellular health, but it is only one piece of the puzzle. NAD3 not only boosts NAD+ levels but also significantly enhances mitochondrial capacity, increasing ATP production by 50% compared to standard NAD+ supplements. This is crucial because mitochondrial capacity determines how efficiently our cells produce energy. NAD3 also activates mitochondrial sirtuins SIRT3, SIRT4, and SIRT5, which are known to suppress age-related issues such as hearing loss, cardiac fibrosis, and cancer. Boosting mitochondrial function with NAD3 rejuvenates cells, making them function like younger cells and providing a sustained, pure energy surge reminiscent of youthful vitality. Additionally, elevated NAD+ levels support DNA repair, enhance metabolic functions, and improve cellular resilience against stress and aging, further promoting overall health and longevity.

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HUMAN TRIALS AVAILABLE

Lowering NLRP3 levels with NAD3 offers substantial health benefits, primarily by reducing chronic inflammation, which is a key factor in the development of numerous diseases, including cardiovascular diseases, neurodegenerative disorders, and autoimmune conditions. NLRP3 is a crucial component of the inflammasome, a protein complex that triggers inflammatory responses. By inhibiting NLRP3, NAD3 helps to prevent the excessive activation of the immune system, thereby minimizing tissue damage and inflammation. This reduction in inflammation can lead to improved overall health, enhanced immune system balance, and a lower risk of chronic diseases. Additionally, by managing NLRP3 levels, NAD3 supports better cellular health and longevity, promoting a healthier, more resilient body.

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A Message From

Dr. Michael Setareh

Medical Director, TRU MD

Backed by Real Science
Doctor Recommended
Clinically Proven Human Trials

TRY NAD3 RISK FREE

MONEY BACK GUARANTEE

Experience Every Benefit of NAD3

Within 12 weeks*

Boost NAD+ Levels within 24 hours! (More Energy)

NAD3 enhances NAD+ levels by 50% within 24 hours, improving cellular energy production and mitochondrial function. This rejuvenates cells, helping them act younger and more efficiently. Unlike caffeine, NAD3 delivers pure, sustained energy, leaving you focused and revitalized throughout the day. Boost your vitality naturally with this cutting-edge formula.*

Higher Stem Cell Levels in 3 Days (Heal Faster)

In just 3 days, NAD3 increases stem cell levels, helping your body heal and regenerate faster. Stem cells replace damaged cells, promote healthy tissue growth, and reduce inflammation. NAD3 ensures your recovery is quicker and more complete, supporting overall resilience and well-being.*

Lower LDL Cholesterol & Triglycerides in 3 Weeks!

Reduce LDL cholesterol and triglycerides within 3 weeks. NAD3 promotes healthy lipid metabolism, reducing plaque buildup in arteries and improving circulation. These changes support heart health, enhance longevity, and reduce the risk of cardiovascular complications.*

5x More Effective in Cellular Health

NAD3 is 5x more effective in boosting NAD+ levels, activating Sirtuins, and reducing NLRP3 inflammation. It also enhances antioxidant defenses with NRF-2 activation and supports DNA repair. Together, these mechanisms protect and optimize cellular health, ensuring better long-term vitality.*

Reduces NLRP3 to Lower Cellular Inflammation

NAD3 reduces NLRP3, a key driver of chronic inflammation. By balancing immune responses and protecting against excessive tissue damage, NAD3 supports cellular health, reduces the risk of inflammation-related diseases, and promotes overall resilience and balance.*

Experience
Every Benefit of NAD3

Within 12 weeks*

Boost NAD+ Levels within 24 hours!(More Energy)

Boosting NAD+ is crucial to cellular health. But elevating NAD+ levels is just one part of the equation. Mitochondrial capacity is measured by how much output (ATP) your cells produce. NAD3 has clinically shown to increase Mitochondrial capacity by 50% over the standard NAD+ supplement. Along with boosting NAD+ levels, NAD3 activates localized mitochondrial sirtuins SIRT3, SIRT4, and SIRT5. This group of sirtuins is known to suppress the emergence of diverse age-related pathologies: hearing loss, cardiac fibrosis, and malignancy. Studies show that boosting mitochondrial function rejuvenates your cells so they start operating as if they were younger cells again. Along with this comes a surge of controlled energy. Unlike that from caffeinated drinks, the energy from NAD3 is pure, similar to that energy you had when you were young*.

Higher Stem Cell Levels in 3 Days (Heal Faster)

Stem cells are crucial for healing due to their unique abilities to regenerate and differentiate into various cell types, replace damaged cells, and promote tissue repair. Their plasticity allows them to transform into different cell types needed for specific tissues, while their paracrine effects involve secreting growth factors and cytokines that reduce inflammation and enhance repair. Additionally, stem cells have anti-inflammatory properties that modulate the immune response and prevent further damage, promote the formation of healthy tissue over scar tissue, and accelerate the healing process, leading to better functional outcomes and faster recovery. These properties make stem cells a vital focus in regenerative medicine and therapeutic treatments for various injuries and diseases.

Lower LDL Cholesterol & Triglycerides in 3 Weeks!

Lowering LDL cholesterol and triglycerides with NAD3 offers significant health benefits, including reduced risk of cardiovascular disease, improved blood vessel health, and enhanced metabolic health. By preventing plaque buildup in arteries and improving blood flow, it lowers the risk of heart attacks and strokes. Additionally, healthy lipid levels aid in better weight management, reduce the risk of obesity-related issues, and prevent fatty liver disease, promoting better liver function. These improvements contribute to increased longevity and a higher quality of life. NAD3 supports these benefits by enhancing cellular energy production, promoting healthy lipid metabolism, and reducing inflammation, making it a valuable supplement for cardiovascular and metabolic health.

5x More Effective in Cellular Health

NAD3 is five times more effective in promoting cellular health due to its comprehensive mechanism of action that includes activating NAD+ levels, which is crucial for cellular energy production and DNA repair. It also activates Sirtuins, a family of proteins that play a key role in aging, inflammation reduction, and metabolic regulation. Additionally, NAD3 lowers NLRP3, a component of the inflammasome linked to chronic inflammation and various diseases. It further boosts NRF-2, a protein that regulates antioxidant responses and protects against oxidative stress, and activates the P27 protein, which is involved in cell cycle regulation and preventing abnormal cell growth. Together, these actions make NAD3 a powerful enhancer of cellular health, offering robust protection and improvement of cellular functions.

Reduces NLRP3 to lower Cellular Inflammation

This Is Why NAD3 is Better Than The Rest

Never mind the fact we're the only NAD+ Booster® Dietary Supplement proven to work with real life benefits

(And not just some numbers on a graph)

This Is Why NAD3 is Better Than The Rest

Never mind the fact we're the only NAD+ Booster®
Dietary Supplement proven to work with real life
benefits

(And not just some numbers on a graph)

RECOMMENDED BY

Top Medical Experts & Pro Athletes

Dr. Michael Setareh

Board Certified Medical Doctor & Medical Director | TRU MD

"This is the most innovative supplement on the market to date. If I had to pick only one supplement to take daily, it would be NAD3. The science and proven benefits behind NAD3 make it a no brainer. I take it. My patients take it. It's a life changing product."

Dr. Martina Randall

Board-Certified Foot and Ankle Surgeon | Sports Medicine Specialist

"NAD3 is the perfect addition to any self-care routine. While treatments like massages or stretches focus on the surface, NAD3 works from within to support bone strength, joint mobility, and reduce inflammation—keeping you active and resilient. A must-have for true rejuvenation."

Nick Urankar

5x CrossFit Games Athlete & CEO of The Zeus Method

"When it comes to performing at the peak of your abilities, every choice matters. That's why my partnership with High Performance Nutrition (HPN) isn't just another endorsement. It's a testament to our shared values and commitment to excellence."

Clark Bartram

America's Most Trusted Fitness Expert & CEO of The CBX Method

"With age comes wisdom, but with wisdom should also come the clarity of choices. HPN's commitment to clean, effective, and premium quality supplements echoes my philosophy: It's not about defying age, but embracing it with strength, grace, and vitality."

Frank Medrano

World Renowned Calisthenics Expert & CEO of The BluePrint

"HPN aligns perfectly with my dedication to clean, effective, and holistic approaches to fitness. My journey has been about mastering my own body through calisthenics and a plant-based diet, and HPN's commitment to high-quality supplements resonates deeply with me."

RECOMMENDED BY

Top Medical Experts
& Pro Athletes

Dr. Michael Setareh

Board Certified Medical Doctor & Medical Director | TRU MD

"This is the most innovative supplement on the market to date. If I had to pick only one supplement to take daily, it would be NAD3. I take it. My patients take it. It's a life changing product."

Dr. Martina Randall

Board-Certified Foot and Ankle Surgeon | Sports Medicine Specialist

Nick Urankar

5x CrossFit Games Athlete & CEO of The Zeus Method

"When it comes to performing at the peak of your abilities, every choice matters. That's why my partnership with HPN isn't just another endorsement. It's a testament to our shared values."

Clark Bartram

America's Most Trusted Fitness Expert & CEO of The CBX Method

"With age comes wisdom, but with wisdom should also come clarity. HPN's commitment to quality echoes my philosophy: Embrace age with strength and vitality."

Frank Medrano

World Renowned Calisthenics Expert & CEO of The BluePrint

"HPN aligns perfectly with my dedication to holistic fitness. Their high-quality supplements resonate deeply with my philosophy: mastery through clean, effective, and innovative approaches."