Best NAD+ Booster® of 2024

We Tested and Reviewed the Top NAD+ Boosters for Anti-Aging and Cellular Health

Anti-Aging Specialist, Dr. Michael Setareh reviews the top selling NAD+ Booster on the market.

As a doctor with years of experience in wellness and anti-aging medicine, I’ve spent countless hours researching ways to slow the aging process and improve overall health. One of the most exciting developments I’ve come across is the role of NAD+ in cellular health and longevity. Boosting NAD+ levels has been shown to improve energy, repair DNA, enhance skin elasticity, and even support mental clarity.

However, with so many NAD+ boosters on the market, it can be overwhelming to determine which ones actually work. Not all products are created equal—and many fall short of delivering the results they promise.

That’s why my team and I tested the top NAD+ boosters available today, so you don’t have to. After conducting extensive research and trials, I’ve narrowed down the best products that actually deliver real, measurable benefits.

Here are the results of our findings, so you can make an informed decision and invest in a product that truly works.

Here’s What to Look for in a High-Quality NAD+ Booster

  1. Advanced Formula Backed by Clinical Trials – Look for NAD+ boosters that go beyond basic formulas and are supported by human clinical data. Products with proven results show clear advantages in cellular health, anti-aging, and energy production.

  2. Sirtuin Activation – Sirtuins are proteins that play a critical role in cellular repair and longevity. A superior NAD+ booster will activate these proteins to help repair DNA, reduce inflammation, and improve cellular function.

  3. Multi-Pathway Approach – Effective products address multiple pathways to optimize NAD+ production and its utilization in the body. They should boost NAD+ levels while also addressing factors like inflammation and oxidative stress.

  4. Transparency and Ingredients – The best NAD+ boosters use premium, science-backed ingredients and are transparent about their formulations. Avoid products with proprietary blends that hide dosing information.

  5. Absorption and Bioavailability – An effective NAD+ booster should include ingredients designed to improve absorption and ensure the body can efficiently utilize the supplement.

  6. Safety and Tolerability – High-quality products are tested for safety and should be free of unnecessary additives or fillers.

What You Will Learn


  • How to Boost NAD+ Levels for Youthful Energy and Cellular Health
  • The Key Features of Top NAD+ Boosters

  • Why Multi-Pathway Approaches Are Essential For Anti-Aging

  • How to Choose the Right NAD+ Booster for Your Needs

  • Where to Find the Best Deals on NAD3

About The Doctor


Dr. Michael Setareh

Expert in Integrative Medicine & Longevity

Dr. Michael Setareh is a renowned specialist in Integrative Medicine and Longevity, with a focus on cutting-edge anti-aging research & treatment protocols. Through years of experience in his real-world medical practice with innovative treatment methods, Dr. Setareh has helped countless patients unlock their full potential through advanced health strategies. As our blog author, he provides readers with actionable insights, the latest research on aging, and practical tips for optimizing wellness. His goal is to inspire others to live healthier, more vibrant lives by embracing science-backed solutions.

Supplement Informant's Top Choice for 2024


NAD3 by High Performance Nutrition

Overall Rating: Excellent

Here Are Our Top Choices for NAD+ Boosters in 2024

1. NAD3 by HPN

NAD3 takes the top spot as the most advanced NAD+ booster on the market today. During the testing process, NAD3 stood out for its ability to improve cellular health in multiple ways. Our testing showed that it boosts NAD+ levels naturally while also activating Sirtuins to repair DNA, reduce inflammation, and elevate key longevity markers such as NRF-2 and P27.

MSRP: $52.99
HOLIDAY SPECIAL PRICE (Save 20%)

only $42.00

Another standout feature of NAD3 is its clinically backed ability to deliver results in a short timeframe. Clinical trials revealed that NAD3 improves lipid profiles by lowering LDL cholesterol and triglycerides in just 12 weeks and increases stem cell activity within three days. This comprehensive approach ensures that NAD3 not only boosts NAD+ levels but also enhances overall cellular health.

If you struggle with signs of aging, fatigue, or inflammation, NAD3 is an excellent solution for rejuvenating your body and optimizing your health from the inside out.

High Performance Nutrition is offering an exclusive sale with significant discounts on NAD3 for a limited time! Click Here to learn more!

NAD3 is not just a simple NAD+ booster—it’s a comprehensive cellular health supplement. Its formula includes ingredients proven to:

  • Boost NAD+ levels naturally without relying on precursors like NR (nicotinamide riboside).
  • Activate Sirtuins to promote DNA repair and cellular rejuvenation.
  • Reduce inflammation by lowering NLRP3, a key driver of aging.
  • Enhance antioxidant defense by boosting NRF-2 levels.
  • Support cellular energy production by elevating mitochondrial function & efficiency.

Clinical trials have shown that NAD3 can:

  • Reduce LDL cholesterol and triglycerides in just 12 weeks.
  • Elevate stem cell activity within 3 days.
  • Improve markers of cellular repair and longevity.

These results make NAD3 a groundbreaking solution for anyone looking to slow aging and enhance their health from the inside out.

PROS CONS
  • Multi-pathway approach for comprehensive cellular health.
  • Backed by 4 human clinical trials.
  • 5x more effective than traditional NAD+ boosters like NR and NMN.
  • Safe, all-natural formula with no fillers.
  • Noticeable results within weeks.
  • Sells out quickly due to high demand.
  • Only available online.

2. TRU Niagen

TRU Niagen is a well-known NAD+ booster that uses NR (nicotinamide riboside) as its primary ingredient. While NR has been shown to boost NAD+ levels, it lacks the multi-pathway approach seen in more advanced products like NAD3.

MSRP: $49
NO KNOWN PROMOTION AVALABLE

PROS CONS
  • Backed by multiple studies showing increases in NAD+ levels.
  • Simple, straightforward formula.
  • Relies solely on NR, which may not work as well for everyone.
  • Does not address inflammation or Sirtuin activation.
  • Limited clinical evidence on long-term anti-aging benefits.

3. Rho Liposomal NAD+ Booster

Rho Liposomal NAD+ Booster uses liposomal delivery to improve the absorption of NAD+ precursors. While this approach enhances bioavailability, it falls short in addressing multiple pathways like Sirtuin activation and inflammation reduction.

MSRP: $55.95
NO KNOWN PROMOTION AVALABLE

PROS CONS
  • Liposomal delivery may improve absorption.
  • Some prefer a liquid versus a capsule but taste might be an issue.
  • Contains synthetic NAD, which has shown limited uptake potential when consumed orally
  • Focuses primarily on absorption without additional cellular health benefits.
  • Limited clinical data on its efficacy.

4. Reus Research NAD+ Booster

Reus Research offers a basic NAD+ booster formula with NR. While it’s a decent option, it lacks the comprehensive approach of NAD3 and has minimal clinical data to support its claims.

MSRP: $59.99
NO KNOWN PROMOTION AVALABLE

PROS CONS
  • Multi-Ingredient Formula.
  • Affordable.
  • Limited clinical data.
  • Contains the unproven and untested Hydrogen Malate form of NR
  • Under-dosed secondary ingredients make the formula unlikely to provide benefits beyond NAD+ production.

Conclusion

After testing and reviewing the most popular NAD+ boosters, it’s clear that NAD3 stands out as the best option for comprehensive anti-aging and cellular health. Unlike its competitors, NAD3 addresses multiple pathways to deliver results that go beyond simply boosting NAD+ levels. Its scientifically-backed formula makes it the most effective solution for anyone serious about slowing the aging process and improving their overall well-being.

While products like TRU Niagen and Elysium Health’s Basis have their merits, they fall short in offering the holistic benefits provided by NAD3. If you’re ready to take your health and anti-aging journey to the next level, NAD3 is the clear choice.

About Dr. Micheal Setareh

Dr. Michael Setareh is a renowned specialist in Integrative Medicine and Longevity, with a focus on cutting-edge anti-aging research & treatment protocols. Through years of experience in his real-world medical practice with innovative treatment methods, Dr. Setareh has helped countless patients unlock their full potential through advanced health strategies. As our blog author, he provides readers with actionable insights, the latest research on aging, and practical tips for optimizing wellness. His goal is to inspire others to live healthier, more vibrant lives by embracing science-backed solutions.

 

Best NAD+ Booster® of 2024

Dr. Michael Setareh & Testing Team | December 11, 2024 | Views: 453760

We Tested and Reviewed the Top NAD+ Boosters for Anti-Aging and Cellular Health

Anti-Aging Specialist, Dr. Michael Setareh reviews the top selling NAD+ Booster on the market.

As a doctor with years of experience in wellness and anti-aging medicine, I’ve spent countless hours researching ways to slow the aging process and improve overall health. One of the most exciting developments I’ve come across is the role of NAD+ in cellular health and longevity. Boosting NAD+ levels has been shown to improve energy, repair DNA, enhance skin elasticity, and even support mental clarity.

However, with so many NAD+ boosters on the market, it can be overwhelming to determine which ones actually work. Not all products are created equal—and many fall short of delivering the results they promise.

That’s why my team and I tested the top NAD+ boosters available today, so you don’t have to. After conducting extensive research and trials, I’ve narrowed down the best products that actually deliver real, measurable benefits.

Here are the results of our findings, so you can make an informed decision and invest in a product that truly works.

Here’s What to Look for in a High-Quality NAD+ Booster

  1. Advanced Formula Backed by Clinical Trials – Look for NAD+ boosters that go beyond basic formulas and are supported by human clinical data. Products with proven results show clear advantages in cellular health, anti-aging, and energy production.

  2. Sirtuin Activation – Sirtuins are proteins that play a critical role in cellular repair and longevity. A superior NAD+ booster will activate these proteins to help repair DNA, reduce inflammation, and improve cellular function.

  3. Multi-Pathway Approach – Effective products address multiple pathways to optimize NAD+ production and its utilization in the body. They should boost NAD+ levels while also addressing factors like inflammation and oxidative stress.

  4. Transparency and Ingredients – The best NAD+ boosters use premium, science-backed ingredients and are transparent about their formulations. Avoid products with proprietary blends that hide dosing information.

  5. Absorption and Bioavailability – An effective NAD+ booster should include ingredients designed to improve absorption and ensure the body can efficiently utilize the supplement.

  6. Safety and Tolerability – High-quality products are tested for safety and should be free of unnecessary additives or fillers.

 

Here Are Our Top Choices for NAD+ Boosters in 2024

1. NAD3 by HPN

NAD3 takes the top spot as the most advanced NAD+ booster on the market today. During the testing process, NAD3 stood out for its ability to improve cellular health in multiple ways. Our testing showed that it boosts NAD+ levels naturally while also activating Sirtuins to repair DNA, reduce inflammation, and elevate key longevity markers such as NRF-2 and P27.

MSRP: $52.99
HOLIDAY SPECIAL PRICE (Save 20%)

only $42.00

Another standout feature of NAD3 is its clinically backed ability to deliver results in a short timeframe. Clinical trials revealed that NAD3 improves lipid profiles by lowering LDL cholesterol and triglycerides in just 12 weeks and increases stem cell activity within three days. This comprehensive approach ensures that NAD3 not only boosts NAD+ levels but also enhances overall cellular health.

If you struggle with signs of aging, fatigue, or inflammation, NAD3 is an excellent solution for rejuvenating your body and optimizing your health from the inside out.

High Performance Nutrition is offering an exclusive sale with significant discounts on NAD3 for a limited time! Click Here to learn more!

NAD3 is not just a simple NAD+ booster—it’s a comprehensive cellular health supplement. Its formula includes ingredients proven to:

  • Boost NAD+ levels naturally without relying on precursors like NR (nicotinamide riboside).
  • Activate Sirtuins to promote DNA repair and cellular rejuvenation.
  • Reduce inflammation by lowering NLRP3, a key driver of aging.
  • Enhance antioxidant defense by boosting NRF-2 levels.
  • Support cellular energy production by elevating mitochondrial function & efficiency.

Clinical trials have shown that NAD3 can:

  • Reduce LDL cholesterol and triglycerides in just 12 weeks.
  • Elevate stem cell activity within 3 days.
  • Improve markers of cellular repair and longevity.

These results make NAD3 a groundbreaking solution for anyone looking to slow aging and enhance their health from the inside out.

PROS:

  • Multi-pathway approach for comprehensive cellular health.
  • Backed by 4 human clinical trials.
  • 5x more effective than traditional NAD+ boosters like NR and NMN.
  • Safe, all-natural formula with no fillers.
  • Noticeable results within weeks.

 

CONS:

  • Sells out quickly due to high demand.
  • Only available online.

2. TRU Niagen

TRU Niagen is a well-known NAD+ booster that uses NR (nicotinamide riboside) as its primary ingredient. While NR has been shown to boost NAD+ levels, it lacks the multi-pathway approach seen in more advanced products like NAD3.

MSRP: $49
NO KNOWN PROMOTION AVALABLE

 

PROS:

  • Backed by multiple studies showing increases in NAD+ levels.
  • Simple, straightforward formula.

CONS:

  • Relies solely on NR, which may not work as well for everyone.
  • Does not address inflammation or Sirtuin activation.
  • Limited clinical evidence on long-term anti-aging benefits.

3. Rho Liposomal NAD+ Booster

Rho Liposomal NAD+ Booster uses liposomal delivery to improve the absorption of NAD+ precursors. While this approach enhances bioavailability, it falls short in addressing multiple pathways like Sirtuin activation and inflammation reduction.

MSRP: $55.95
NO KNOWN PROMOTION AVALABLE

PROS:

  • Liposomal delivery may improve absorption.
  • Some prefer a liquid versus a capsule but taste might be an issue.

CONS:

  • Contains synthetic NAD, which has shown limited uptake potential when consumed orally
  • Focuses primarily on absorption without additional cellular health benefits.
  • Limited clinical data on its efficacy.

4. Reus Research NAD+ Booster

Reus Research offers a basic NAD+ booster formula with NR. While it’s a decent option, it lacks the comprehensive approach of NAD3 and has minimal clinical data to support its claims.

MSRP: $59.99
NO KNOWN PROMOTION AVALABLE

PROS:

  • Multi-Ingredient Formula.
  • Affordable.

CONS:

  • Limited clinical data.
  • Contains the unproven and untested Hydrogen Malate form of NR
  • Under-dosed secondary ingredients make the formula unlikely to provide benefits beyond NAD+ production.

Conclusion

After testing and reviewing the most popular NAD+ boosters, it’s clear that NAD3 stands out as the best option for comprehensive anti-aging and cellular health. Unlike its competitors, NAD3 addresses multiple pathways to deliver results that go beyond simply boosting NAD+ levels. Its scientifically-backed formula makes it the most effective solution for anyone serious about slowing the aging process and improving their overall well-being.

While products like TRU Niagen and Elysium Health’s Basis have their merits, they fall short in offering the holistic benefits provided by NAD3. If you’re ready to take your health and anti-aging journey to the next level, NAD3 is the clear choice.

About Dr. Micheal Setareh

Dr. Michael Setareh is a renowned specialist in Integrative Medicine and Longevity, with a focus on cutting-edge anti-aging research & treatment protocols. Through years of experience in his real-world medical practice with innovative treatment methods, Dr. Setareh has helped countless patients unlock their full potential through advanced health strategies. As our blog author, he provides readers with actionable insights, the latest research on aging, and practical tips for optimizing wellness. His goal is to inspire others to live healthier, more vibrant lives by embracing science-backed solutions.